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International Journal of Epidemiology 2002;31:285-293
© International Epidemiological Association 2002


Editorial

A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives

Yoav Ben-Shlomoa and Diana Kuhb

a Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK.
b Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, University College London Medical School, 1–19 Torrington Place, London WC1E 6BT, UK.

Yoav Ben-Shlomo.

What is a Life Course Approach to Chronic Disease Epidemiology?

Over the last few years there has been increasing interest in conceptualizing disease aetiology within a life course framework.1,2 This approach is not new to Public Health or unique to epidemiology (see below). However, its current resonance and interest within epidemiology reflects the challenging theoretical framework this approach provides. This issue of the International Journal of Epidemiology has several papers with a ‘life course theme’. This accompanying editorial is intended to highlight what we believe are the key conceptual issues around life course epidemiology. We have chosen to use examples from chronic disease epidemiology, but this approach is also applicable within the context of infectious diseases3 and wider notions of health and wellbeing.4

We have defined a life course approach to chronic disease epidemiology1 as the study of long-term effects on chronic disease risk of physical and social exposures during gestation, childhood, adolescence, young adulthood and later adult life. It . . . [Full Text of this Article]

Conceptual Models in Life Course Epidemiology

How ‘Critical’ is a Critical Period?

Critical Versus Sensitive Periods

From Individual to Inter-generational and Population Determinants of Health

Other Epidemiological Paradigms

Putting Life Course in a Historical and Inter-disciplinary Context

Epidemiology
Other scientific disciplines
Empirical Challenges in Undertaking Life Course Analyses

Conclusions

Acknowledgments

References


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Int J EpidemiolHome page
S. M. Morton
Commentary: The child is the mother of the woman: Intergenerational associations in maternal anthropometry
Int. J. Epidemiol., December 1, 2004; 33(6): 1249 - 1251.
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Epidemiol RevHome page
B. Galobardes, J. W. Lynch, and G. Davey Smith
Childhood Socioeconomic Circumstances and Cause-specific Mortality in Adulthood: Systematic Review and Interpretation
Epidemiol. Rev., July 1, 2004; 26(1): 7 - 21.
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J. Epidemiol. Community HealthHome page
O. Naess, B. Claussen, and G. Davey Smith
Relative impact of childhood and adulthood socioeconomic conditions on cause specific mortality in men
J Epidemiol Community Health, July 1, 2004; 58(7): 597 - 598.
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J. Epidemiol. Community HealthHome page
O. Naess, B. Claussen, D. S Thelle, and G. Davey Smith
Cumulative deprivation and cause specific mortality. A census based study of life course influences over three decades
J Epidemiol Community Health, July 1, 2004; 58(7): 599 - 603.
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HeartHome page
D A Lawlor, M Taylor, G Davey Smith, D Gunnell, and S Ebrahim
Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health study
Heart, July 1, 2004; 90(7): 745 - 749.
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Am J EpidemiolHome page
J. Merlo, K. Asplund, J. Lynch, L. Rastam, and A. Dobson
Population Effects on Individual Systolic Blood Pressure: A Multilevel Analysis of the World Health Organization MONICA Project
Am. J. Epidemiol., June 15, 2004; 159(12): 1168 - 1179.
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Int J EpidemiolHome page
R. Lund, B. E. Holstein, and M. Osler
Marital history from age 15 to 40 years and subsequent 10-year mortality: a longitudinal study of Danish males born in 1953
Int. J. Epidemiol., April 1, 2004; 33(2): 389 - 397.
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JAMAHome page
N. Halfon and M. Inkelas
Optimizing the Health and Development of Children
JAMA, December 17, 2003; 290(23): 3136 - 3138.
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Int J EpidemiolHome page
J. Lynch, S. Harper, and G. Davey Smith
Commentary: Plugging leaks and repelling boarders--where to next for the SS Income Inequality?
Int. J. Epidemiol., December 1, 2003; 32(6): 1029 - 1036.
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