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IJE Advance Access published online on November 24, 2009
International Journal of Epidemiology, doi:10.1093/ije/dyp331
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2009; all rights reserved.

Quasi-experimental evidence on the causal effects of physical health on mental health

Manoj Mohanan1 and Joanna Maselko2,*

1Duke Global Health Institute, Duke University, Durham, NC, USA.
2Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.

* Corresponding author: Duke Global Health Institute, Duke University, 114 Trent Hall, Trent Drive, Box 90519, Durham, NC 27708, USA. E-mail: Joanna.maselko{at}duke.edu


  Abstract

Background While a large body of literature has demonstrated an association between physical health problems and psychiatric ones, the extent to which one is causally linked to the other remains difficult to estimate. This quasi-experimental study seeks to (i) estimate causal effects of an acute negative health event (health shock) on mental health and (ii) examine the role of debt and disability as potential mediators.

Methods The study design employs exogenous injuries in bus accidents together with a matching procedure to simulate a random exposure to physical health shock. The study was conducted among travellers on state-owned buses in Karnataka, India. Exposure occurred between July and December 2005. Outcomes were assessed from a household survey conducted in November–December 2006. Eighty-four injured passengers identified from bus accident compensation records were interviewed along with 336 unexposed individuals enrolled from passengers on the same accident bus routes, matched on age group, gender and village/neighbourhood of residence. The main outcome of Psychological Distress was measured using the Kessler-10 scale.

Results Exposure to the health shock increases psychological distress by 1.5 standard deviations (SD) 1 year later (P < 0.01). Physical disability is a key mediating mechanism, accounting for 65% of the observed effect. After controlling for disability, odds of having distress levels commensurate with moderate/severe mental illness was 3.01 [95% confidence interval (CI) 1.26–7.19]. Indebtedness resulting from the health shock did not mediate the association between shock and distress.

Conclusion Evidence from this quasi-experimental study supports the hypothesis that acute physical health shocks can cause long-term mental health problems.

Keywords Mental health, causal effect, quasi-experimental, injury, disability

Accepted 30 September 2009


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