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IJE Advance Access first published online on January 24, 2007
This version published online on April 12, 2007

International Journal of Epidemiology, doi:10.1093/ije/dyl294
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© The Author 2007; all rights reserved.
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org Published by Oxford University Press on behalf of the International Epidemiological Association

Alcohol accounts for a high proportion of premature mortality in central and eastern Europe

Jürgen Rehm1–4,{dagger},*, Urszula Sulkowska1, Marta Manczuk1, Paolo Boffetta5, John Powles6, Svetlana Popova2 and Witold Zatonski1

1Cancer Center and Institute of Oncology, Cancer Epidemiology and Prevention Division, Warsaw, Poland.
2Centre for Addiction and Mental Health, Toronto, Canada.
3Research Institute for Public Health and Addiction, Zurich, Switzerland.
4Institut für Klinische Psychologie und Psychotherapie, TU Dresden, Germany.
5International Agency for Research on Cancer, Lyon, France.
6Institute of Public Health, Cambridge, UK.

* Corresponding author. Centre for Addiction and Mental Health, 33 Russell Street, room 2035B, Toronto, ON M5S 2S1 Canada. E-mail: jtrehm{at}aol.com


   Abstract

Background There is a west–east mortality gradient in Europe, more pronounced in men. The objective of this article was to quantify the contribution of alcohol use to the gap in premature adult mortality between three old (France, Sweden and United Kingdom) and four new (Czech Republic, Hungary, Lithuania and Poland) European Union (EU) member states for the year 2002. Russia was added as an external comparator.

Methods Exposure data were taken from surveys and per capita consumption records from the World Health Organization (WHO) Global Alcohol Database. Mortality data were taken from the WHO databank. The risk relationships were taken from published meta-analyses and from the WHO Comparative Risk Assessment project. Alcohol exposure and relative risk information was combined to derive alcohol-attributable fractions for relevant causes of premature mortality.

Results Alcohol consumption was responsible for 14.6% of all premature adult mortality in the eight countries, 17.3% in men and 8.0% in women. This proportion was clearly higher in the new EU member states and Russia compared with the comparison countries from the old EU. For men, Russia with 29.0 alcohol-attributable premature deaths per 10 000 population had a more than 10-fold higher rate compared with Sweden (2.7 deaths/10 000). For women, the ratio between Hungary (5.0 alcohol-attributable deaths/10 000) and Russia (4.7 deaths/10 000) compared with Sweden (0.5 deaths/10 000) was almost as high, but the rates were much lower. The Czech Republic and Poland showed proportionally less alcohol-attributable premature mortality than the other new EU member states or Russia for both genders, which, however, was still higher than in any of the old EU member states.

Conclusions Alcohol is a strong contributor to the health gap between western and central and eastern Europe, with both average volume of consumption and patterns of drinking contributing to burden of disease and injury. Alcohol also contributes substantially to male–female differences in mortality and life expectancy. However, there are feasible and cost-effective measures to reduce alcohol-related burden that should be implemented in central and eastern Europe.

Keywords Premature mortality, alcohol consumption, drinking behaviour, central and eastern Europe


{dagger}Work for this contribution was mainly undertaken while the first author stayed at the Cancer Center in Warsaw, Poland.

Accepted 6 December 2006


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