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© 1979 Oxford University Press

research-article

Poliomyelitis, Rubella, and Dengue Antibody Survey in Barbados. A Follow-up Study

A S EVANS1, A V WELLS2, F RAMSAY2, P DRABKIN1 and K PALMER1

1Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
2Ministry of Health, Bridgetown, Barbados, WI

Evans A S [Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA], Wells A V, Ramsay F, Drabkin P and Palmer K. Poliomyelitis, rubella and dengue antibody survey in Barbados. A follow-up study. International Journal of Epidemiology 1979, 8: 235–241.

A follow-up study of poliomyelitis, rubella, and dengue antibodies has been made in light of results obtained in a 1972 health and serological survey in Barbados, W. I. Poliomyelitis antibody neutralization tests performed on sera from 307 children under age 15 using overnight serum/virus mixtures on microtiter plates at low serum dilutions revealed the absence of polio antibody at 1: 2 dilution in 13.7% for type 1, 6.5% for type 2, and 14.3% for type 3 virus. A significant correlation of the presence or absence of poliomyelitis antibody to types 2 and 3 was seen with the response to immunization histories. Forty-three of 49 girls (88%) given rubella vaccine (RA 27/3) in 1972 had demonstrable haemagglutination-inhibition antibody 4 years later. Neutralization tests for dengue antibody confirmed the results of the complement-fixation tests and indicated that type 2 was probably the sole infecting strain.

Received 6 June 1979


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