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© 1978 Oxford University Press

research-article

Viral Hepatitis: Lack of Transmission in an Athenian School

G PAPAEVANGELOU1, J W MOSLEY2, A KYRIAKIDOU3 and V M EDWARDS4

1, 3 Department of Epidemiology, Athens School of Hygiene 52 Skoufa Street, Athens, Greece.
2, 4 Department of Medicine, University of Southern California School of Medicine Los Angeles, California 90007, USA.

In the 1975–76 school year, 3 cases of icteric hepatitis occurred almost simultaneously in 2 grades of an Athenian school. An initial survey of the 2 classes approximately one week later found that 88 of 94 children were susceptible to type A hepatitis. No further clinical cases occurred. A second survey at the end of the school year revealed only 2 subclinical hepatitis A virus infections: one coincident with the over cases in November, and a second from extramural exposure in February. Two carriers of hepatitis B virus in class A were not associated with serologic evidence for communicability of that agent in this setting. Testing of faecal specimens for agents possibly responsible for epidemiological interference with the spread of hepatitis A virus was unsuccessful. Nevertheless, the hypothesis of Bang that other agents may interfere with transmission of hepatitis A virus deserves further study.

Received 4 September 1978


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