IJE Advance Access originally published online on April 17, 2007
International Journal of Epidemiology 2007 36(3):560-566; doi:10.1093/ije/dym060
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Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men
1Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, Rowland Hill Street, London NW3 2PF, UK.
2Department of Community Health Sciences, St George's University of London, London SW17 0RE, UK.
* Corresponding author. Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, Rowland Hill Street, London NW3 2PF, UK. E-mail: s.ramsay{at}pcps.ucl.ac.uk
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Abstract |
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Background The independent influence of childhood social circumstances on health in later life remains uncertain. We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors.
Methods A socio-economically representative sample of 5552 British men (52–74 years) with retrospective assessment of childhood socio-economic circumstances (father's occupation and childhood household amenities) who were followed up for CHD (fatal and non-fatal) for 12 years.
Results Men whose childhood social class was manual had an increased hazard ratio (HR) 1.34 (95% CI 1.11–1.63)—this effect was diminished when adjusted for adult social class and adult behavioural risk factors (cigarette smoking, alcohol, physical activity and body weight) (HR 1.19; 95% CI 0.97–1.46). Men whose family did not own a car in their childhood were at increased CHD risk even after adjustments for adult social class and behaviours (HR 1.35, 95% CI 1.04–1.75). Men with combined exposure to both childhood and adult manual social class had the highest risk of CHD (HR 1.51; 95% CI 1.19–1.91); this was substantially reduced by adjustment for adult behavioural risk factors (adjusted HR 1.28; 95% CI 0.99–1.65).
Conclusions Less affluent socio-economic conditions in childhood may have a modest persisting influence on risk of CHD in later life.
Keywords Childhood social circumstances, adult social class, behavioural risk factors, CHD, old age
Accepted 6 March 2007
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