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IJE Advance Access originally published online on September 22, 2006
International Journal of Epidemiology 2006 35(6):1522-1529; doi:10.1093/ije/dyl168
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2006; all rights reserved.

Chronic Disease Epidemiology

Chronic diseases now a leading cause of death in rural India—mortality data from the Andhra Pradesh Rural Health Initiative

Rohina Joshi1,*, Magnolia Cardona1, Srinivas Iyengar2, A Sukumar2, C Ravi Raju2, K Rama Raju2, Krishnam Raju3, K Srinath Reddy4, Alan Lopez5 and Bruce Neal1

1 The George Institute for International Health, PO Box M201, Missenden Road, Sydney NSW 2050, Australia.
2 Byrraju Foundation, Satyam Enclave, 2-74 Jeedimetla Village, NH-7, Hyderabad, Andhra Pradesh 500855, India.
3 CARE Foundation, Banjara Hills, Hyderabad, Andhra Pradesh, India.
4 Centre for Chronic Disease Control, V15 Green Park Extension, New Delhi 110016, India.
5 School of Population Health, University of Queensland, Queensland, Australia.

* Corresponding author: The George Institute for International Health, PO Box M201, Missenden Road, Sydney NSW 2050, Australia. E-mail: rjoshi{at}thegeorgeinstitute.org


   Abstract

Introduction India is undergoing rapid epidemiological transition as a consequence of economic and social change. The pattern of mortality is a key indicator of the consequent health effects but up-to-date, precise, and reliable statistics are few, particularly in rural areas.

Methods Deaths occurring in 45 villages (population 180 162) were documented during a 12-month period in 2003–04 by multipurpose primary healthcare workers trained in the use of a verbal autopsy tool. Algorithms were used to define causes of death according to a limited list derived from the international classification of disease version 10. Causes were assigned by two independent physicians with disagreements resolved by a third.

Results A total of 1354 deaths were recorded with verbal autopsies completed for 98%. A specific underlying cause of death was assigned for 82% of all verbal autopsies done. The crude death rate was 7.5/1000 (95% confidence interval, 7.1–7.9). Diseases of the circulatory system were the leading causes of mortality (32%), with similar proportions of deaths attributable to ischaemic heart disease and stroke. Second was injury and external causes of mortality (13%) with one-third of these deaths attributable to deliberate self harm. Third were infectious and parasitic diseases (12%). Tuberculosis and intestinal conditions each caused one-third of deaths within this category. HIV was assigned as the cause for 2% of all deaths. The fourth and fifth leading causes of death were neoplasms (7%) and diseases of the respiratory system (5%).

Conclusion Non-communicable and chronic diseases are the leading causes of death in this part of rural India. The observed pattern of death is unlikely to be unique to these villages and provides new insight into the rapid progression of epidemiological transition in rural India.


Keywords verbal autopsy, mortality surveillance, cause of death, chronic disease, rural India

Accepted 5 July 2006


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