International Journal of Epidemiology 2002;31:234-239
© International Epidemiological Association 2002
Cardiovascular Disease and Diabetes |
Diabetes in a Caribbean population: epidemiological profile and implications
a School of Clinical Medicine & Research, University of the West Indies.
b Ministry of Health, Barbados, West Indies.
c University Medical Center at Stony Brook, Stony Brook, NY, USA.
d The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
M Cristina Leske, Department of Preventive Medicine, University Medical Center at Stony Brook, HSC L3 086, Stony Brook, NY 11794–8036, USA. E-mail: cleske{at}notes.cc.sunysb.edu
Abstract
Objective To examine the distribution and impact of diabetes, glycaemic status, and related factors, in a predominantly black adult Caribbean population.
Methods The study included 4709 people, or 84% of a simple random sample of Barbadian-born citizens aged 40–84 years, examined between 1988 and 1992 and re-assessed 4 years later. Diabetes was evaluated according to physician-diagnosis and glycosylated haemoglobin (GHb). Associations were assessed by logistic regression analyses, cumulative mortality by product-limit methods and death-rate ratios by Cox proportional hazards regression.
Results Among the 4314 black participants, the prevalence of known diabetes, predominantly type 2, was 9.1% at 40–49 years of age and increased to 24.0% at 70–79 years. The overall prevalence was 17.5%, while it was 12.5% in mixed (black/ white; n = 184) and 6.0% in white/other participants (n = 133), only 0.3% had younger-onset. Additionally, 2% had GHb >10% (>2 SD over the mean) without diabetes history. Sulphonylureas were the most frequent treatment, while insulin use was infrequent. In black participants, diabetes was positively associated with age (OR = 1.03 per year; 95% CI : 1.02–1.04), diabetes family history (OR = 2.85, 95% CI : 2.39–3.40), hypertension (OR = 1.71, 95% CI : 1.42–2.05), obesity (BMI 
25 kg/m2; OR = 1.74, 95% CI : 1.44–2.10), and high waist-hip ratio (WHR 0.92; OR = 1.29, 95% CI : 1.09–1.53). Ocular co-morbidities were increased among people with diabetes, as was 4-year-mortality (death rate ratio = 1.42, 95% CI : 1.10–1.83). There was a 9% increase in mortality for each 1% increase in GHb (death rate ratio = 1.09, 95% CI : 1.04–1.15).
Conclusions A markedly high prevalence of diabetes existed in the adult black population, affecting almost one in five people and increasing morbidity and mortality. Prevention strategies are urgently needed to reduce the adverse implications of diabetes in this and similar populations.
Keywords Type 2 diabetes, morbidity, mortality, Barbados
Accepted 11 July 2001
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  I. Miljkovic-Gacic, C. L Gordon, B. H Goodpaster, C. H Bunker, A. L Patrick, L. H Kuller, V. W Wheeler, R. W Evans, and J. M Zmuda Adipose tissue infiltration in skeletal muscle: age patterns and association with diabetes among men of African ancestry Am. J. Clinical Nutrition, June 1, 2008; 87(6): 1590 - 1595. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. J.M. Hennis, H. S. Fraser, R. Jonnalagadda, J. Fuller, and N. Chaturvedi Explanations for the High Risk of Diabetes-Related Amputation in a Caribbean Population of Black African Descent and Potential for Prevention Diabetes Care, November 1, 2004; 27(11): 2636 - 2641. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. O.C. Corbin, V. Poddar, A. Hennis, A. Gaskin, C. Rambarat, R. Wilks, C. D.A. Wolfe, and H. S. Fraser Incidence and Case Fatality Rates of First-Ever Stroke in a Black Caribbean Population: The Barbados Register of Strokes Stroke, June 1, 2004; 35(6): 1254 - 1258. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Hennis, S.-Y. Wu, B. Nemesure, and M. C. Leske Risk Factors for Incident Cortical and Posterior Subcapsular Lens Opacities in the Barbados Eye Studies Arch Ophthalmol, April 1, 2004; 122(4): 525 - 530. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Hamaguchi, H. Terao, Y. Kusuda, T. Yamashita, J. A. Hazoury Bahles, M. Cruz LL., L. I. Brugal V., B. Jongchong W., H. Yoshimatsu, and T. Sakata The PC-1 Q121 Allele Is Exceptionally Prevalent in the Dominican Republic and Is Associated with Type 2 Diabetes J. Clin. Endocrinol. Metab., March 1, 2004; 89(3): 1359 - 1364. [Abstract] [Full Text] [PDF]
|
|