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International Journal of Epidemiology 2000;29:899-904
© International Epidemiological Association 2000

Birds of a feather: using a rotational box plot to assess ascertainment bias

Stephen Q Mutha, John J Potterata and Richard B Rothenbergb

a El Paso County Department of Health and Environment, Colorado Springs, CO, USA.
b Emory University School of Medicine, Department of Family and Preventive Medicine, Atlanta, GA, USA.

Reprint requests to: Stephen Muth, El Paso County Department of Health and Environment, STD/HIV Programs, 301 South Union Boulevard, Colorado Springs, CO 80910–3123, USA. E-mail: smuth{at}uswest.net

Background Comparability of study participants with non-participants is customarily assessed by contrasting the distributions of sociodemographic characteristics. Such comparisons do not necessarily provide insight into whether or not participants of a given subgroup are similar to non-participants of the same subgroup. A geographical information system (GIS) may provide such insight by visually displaying the spatial distributions of participants and non-participants. In a previously reported study of heterosexuals at elevated risk for human immunodeficiency virus (HIV), traditional methods suggested distributional differences in the demographic characteristics of participants and non-participants.

Methods Based on residential address co-ordinates for each subgroup member, we used the subgroup's centroid as the origin and constructed a 360° series of overlapping box plots of the distance of subgroups members to the origin, thereby producing closed polygons for each of the box plot demarcators.

Results These rotational box plots revealed similar geographical distributions for most participant and non-participant subgroups, with the exception of African-American men and women.

Conclusions Observed differences resulted in part from the study design, and provided some insight into sampling problems encountered in social network studies. Based on Tobler's supposition that ‘nearby things tend to be alike’, the rotational box plot is a useful additional tool for investigating sample bias.

Keywords Geography, geographical information systems (GIS), exploratory spatial data analysis (ESDA), sampling bias

Accepted 24 March 2000


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