International Journal of Epidemiology, Vol 28, 130-134, Copyright © 1999 by International Epidemiological Association
Y Nakamura, H Yanagawa, K Hoshi, H Yoshino, J Urata and T Sato
BACKGROUND: The objective of this study is to clarify the incidence rate of
Creutzfeldt-Jakob disease (CJD) during the last decade in Japan. METHODS: A
nationwide mail survey was conducted in all hospitals with a minimum bed
capacity of 100 and having at least one of three departments: neurology,
psychiatry, and neuropathology. The survey required the patient's sex, date
of birth, date of diagnosis, diagnostic criteria, medical history and CJD
incidence in the family. RESULTS: From 493 hospitals throughout the
country, 821 patients with CJD were reported from January 1985 through
March 1996. The annual incidence rate was 0.49 per million population for
males and 0.68 for females. The age-specific incidence rate was highest
among those 70-79 years of age, followed by the 60-69, and 50-59 age
groups. The incidence and mortality increased during the observed period;
however, the incidence rate among younger generations did not rise.
CONCLUSION: A nationwide incidence survey of CJD in Japan revealed the
incidence and distribution of the disease over the recent decade. It was
found that the incidence and mortality rates had increased during the
observed period.
ARTICLES
Incidence rate of Creutzfeldt-Jakob disease in Japan
Department of Public Health, Jichi Medical School, Minamikawachi, Tochigi, Japan.
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