© 1998 Oxford University Press
research-article |
Mortality of drug addicts in the United Kingdom 19671993
Department of Psychiatry of Addictive Behaviour, St George's Hospital Medical School London SWI7 ORE, UK
BACKGROUND: Mortality m specified clinical populations has often been regarded as a measure of treatment effectiveness. This study examined time trends in mortality of drug addicts in the UK notified to the Home Office over a 27-year period.
METHODS: The study was a longitudinal analysis of routine mortality data of a population of newly notified addicts from 1967 to 1993. Altogether. 92 802 addicts were newly notified during the study period, and they accounted for 687 673 person-years of observation. The math outcome measures were age-specific all-causes mortality; drug-related mortality; and age- and sex-specific standardized mortality ratios (SMR) 19671993.
RESULTS: There were significant differences in death rates between the periods 19671976 (19/1000 person-years) and 19841993 (10.5/1000 person-years). Excess deaths were significantly higher among the 19671976 cohorts than in the 19841993 cohorts (SMR ratio = 1.80, 95% CI: 1.641.97). The majority of deaths were drug-related, with those aged <45 years more likely to die of a drug-related cause than those older (OR = 6.29, 95% CI: 4.977.96).
CONCLUSIONS: It appears that service provision has some impact on all-causes mortality among opiate addicts. As services improved, there was a corresponding dedine in mortality rates during the study period. Further preventive measures, however, should be devised to reduce drug-related deaths.
Keywords Drug dependence, opiate addicts, drug-related mortality, treatment effectiveness
Accepted 8 October 1997
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
M. Hickman, V. Hope, B. Coleman, J. Parry, M. Telfer, J. Twigger, C. Irish, J. Macleod, and H. Annett Assessing IDU prevalence and health consequences (HCV, overdose and drug-related mortality) in a primary care trust: implications for public health action J. Public Health Med., September 1, 2009; 31(3): 374 - 382. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Whitty and J. O'Connor Opiate dependence and pregnancy: 20-year follow-up study Psychiatr. Bull., December 1, 2007; 31(12): 450 - 453. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. L. Mintzer, M. Eisenberg, M. Terra, C. MacVane, D. U. Himmelstein, and S. Woolhandler Treating Opioid Addiction With Buprenorphine-Naloxone in Community-Based Primary Care Settings Ann. Fam. Med, March 1, 2007; 5(2): 146 - 150. [Abstract] [Full Text] [PDF] |
||||
![]() |
L Degenhardt, W Hall, and M Warner-Smith Using cohort studies to estimate mortality among injecting drug users that is not attributable to AIDS Sex Transm Inf, June 1, 2006; 82(suppl_3): iii56 - iii63. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. De Angelis, M. Hickman, and S. Yang Estimating Long-term Trends in the Incidence and Prevalence of Opiate Use/Injecting Drug Use and the Number of Former Users: Back-Calculation Methods and Opiate Overdose Deaths Am. J. Epidemiol., November 15, 2004; 160(10): 994 - 1004. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Copeland, J. Budd, J. R. Robertson, and R. A. Elton Changing Patterns in Causes of Death in a Cohort of Injecting Drug Users, 1980-2001 Arch Intern Med, June 14, 2004; 164(11): 1214 - 1220. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. E Harris, M. E Ramsay, N. Andrews, and K. P Eldridge Clinical course of hepatitis C virus during the first decade of infection: cohort study BMJ, February 23, 2002; 324(7335): 450 - 450. [Abstract] [Full Text] [PDF] |
||||






