International Journal of Epidemiology, Vol 26, 1009-1016, Copyright © 1997 by International Epidemiological Association
J Hansen, P Boffetta, A Andersen, JW Cherrie, J Chang-Claude, U Eilber, R Frentzel-Beyme, T Hemmingsson, JH Olsen, N Plato, R Saracci, GB Skare and P Westerholm
BACKGROUND: Studies of the aetiology of fatal diseases often rely on data
obtained from relatives, which can cause loss of precision and introduce
bias. We assessed the quality of such information on demographics,
occupation, smoking and alcohol habits. METHODS: We compared contemporary
interviews, based on a structured questionnaire, with male workers from the
man-made vitreous fibre production industry in four European countries and
their relatives. The participation rate was 63% (74 pairs of workers and
relatives). RESULTS: Only minor differences in the ability to answer the
questions appeared among workers and relatives, except for specific
occupational questions. There was moderate to excellent agreement for
demographics, residential and work history (kappa or intraclass correlation
range: 0.44-0.98). For smoking habits, beer and wine consumption the
agreement was good to excellent (range: 0.59-0.99). In particular, number
of different residential areas, jobs, industries, and duration of wine
drinking were significantly underreported by the relatives. No general
determinant for reduced agreement appeared. CONCLUSIONS: In general, the
quality of information obtained from relatives appeared good. However,
information on specific occupational exposures may be improved by
supplementing the information from relatives with details obtained from
colleagues, occupational hygiene experts or occupation-exposure matrices.
ARTICLES
Comparison of information on occupation and lifestyle habits obtained from European man-made vitreous fibre production workers and their relatives
International Agency for Research on Cancer, Lyon, France.
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