International Journal of Epidemiology, Vol 26, 867-872, Copyright © 1997 by International Epidemiological Association
HC Boshuizen and S Greenland
BACKGROUND: Current epidemiological methods focus mostly on incidence rates
and their ratios as measures of occurrence and effect. Incidence rates and
rate ratios can be hard to interpret when the outcome disease is common.
METHODS: The possibilities of using an alternative measure, average age at
first occurrence of the disease, are discussed. RESULTS: Methods for the
analysis of average age at first occurrence are illustrated in a study of
occupation and disability pension. We estimate that the average age at
pension among crane drivers is only about 0.8 that of maintenance workers,
regardless of the method, although the confidence intervals depend on the
method. CONCLUSIONS: Average age at first occurrence is easier to interpret
than the incidence rate for a very common disease. Because estimates are
not readily available in software packages, we encourage further
development of packaged software for this measure.
ARTICLES
Average age at first occurrence as an alternative occurrence parameter in epidemiology
Department of Public Health and Prevention, Leiden, The Netherlands.
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