| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
International Journal of Epidemiology, Vol 26, 571-574, Copyright © 1997 by International Epidemiological Association
K Kallen
BACKGROUND: In order to investigate whether an earlier reported association
between maternal smoking during pregnancy and urinary organ malformations
could be confirmed, a study was made using Swedish health registries.
METHODS: Infants with kidney malformations (n = 483) and infants with other
urinary organ malformations with no primary involvement of the kidney(s) (n
= 719) were selected among 1117021 infants born 1983-1993 with known
smoking exposure in early pregnancy. RESULTS: A moderate statistically
significant association between maternal smoking and kidney malformations
was found (adjusted odds ratio [OR] = 1.22, 95% confidence interval [CI] :
1.00-1.48). With the exception of genetic renal polycystic disease, the
main subgroups of kidney malformations showed similar OR. For other urinary
organ malformations, no association with smoking could be detected (OR =
0.93, 95% CI: 0.79-1.11). CONCLUSIONS: This study supports an association
between maternal smoking during pregnancy and kidney malformations. No
obvious confounders were detected but further work is needed before a
causal inference can be made.
ARTICLES
Maternal smoking and urinary organ malformations
Tornblad Institute, Lund, Sweden.
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
E. L. Carmines, C. L. Gaworski, A. S. Faqi, and N. Rajendran In Utero Exposure to 1R4F Reference Cigarette Smoke: Evaluation of Developmental Toxicity Toxicol. Sci., September 1, 2003; 75(1): 134 - 147. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Ritz, F. Yu, S. Fruin, G. Chapa, G. M. Shaw, and J. A. Harris Ambient Air Pollution and Risk of Birth Defects in Southern California Am. J. Epidemiol., January 1, 2002; 155(1): 17 - 25. [Abstract] [Full Text] [PDF] |
||||

