International Journal of Epidemiology, Vol 26, 364-370, Copyright © 1997 by International Epidemiological Association
A Settnes, AP Lange and T Jorgensen
BACKGROUND: The aim has been to assess the gynaecological characteristics
of importance for hysterectomy performed for benign diseases. METHODS: In a
prevalence study, 2301 Danish women aged 30, 40, 50, or 60 years, were
selected at random in 1982, and self-report questionnaires were collected
from 77%. Information about gynaecological and obstetric history, social
background, weight and dieting history, and various lifestyles were
recorded. Weight and height were measured. In an incidence study, the
cohort was followed during 1982-1990 via central registers to assess the
incidence of hysterectomy. Logistic and Cox regression were used to analyse
data. RESULTS: In the prevalence study, 85% of the hysterectomies were
performed for benign conditions. Early menarche (< or = 11 years old)
and short-term use of oral contraceptives (OC) (1-4 years) were independent
correlates of these hysterectomies by multivariate analyses, whereas
multiparity (> or = 4 childbirths) was confounded by education and
weight-related factors. Long-term use of OC was associated with lower
prevalence of hysterectomy. In the incidence study, short-term use of OC
and ever use of progestogen-only minipills were independent risk factors
for hysterectomy performed recently for benign diseases in women under 50
in the multivariate analyses. Abortions did not reach significance, and
neither multiparity, long- term use of OC, nor early menarche were
important. CONCLUSION: The most important gynaecological characteristics
related to premenopausal hysterectomy performed for benign diseases are
hormonal contraceptives. These findings imply that the decision-making
process concerning hysterectomy might depend on women's choice of
contraception and compliance with OC as medical treatment.
ARTICLES
Gynaecological correlates of hysterectomy in Danish women
Department of Internal medicine C, Glostrup University Hospital, Denmark.
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