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© 1995 Oxford University Press

research-article

Prevalence and Sex-Ratio of the Subtypes of Migraine

MICHAEL BJØRN RUSSELL*,{dagger},, BIRTHE KROGH RASMUSSEN*,{dagger}, PER THORVALDSEN* and JES OLESEN{dagger}

* The Glostrup Population Studies, Department of Neurology DK-2600 Glostrup, Denmark.
{dagger} Department of Internal Medicine C, Glostrup Hospital, University of Copenhagen DK-2600 Glostrup, Denmark.

Reprint requests to: Michael BjØrn Russell.

Background. The aim of this study was to provide the prevalence and sex-ratio of subtypes of migraine diagnosed by neurological interview according to the criteria of the International Headache Society.

Methods. In all, 3000 males and 1000 females aged 40 years were randomly selected from the Danish population. They received a mailed questionnaire regarding migraine. The questionnaire response rate was 87%. People with self-reported migraine and a random sample of those reporting no migraine were invited to a headache interview, and a physical and a neurological examination. Those not reacting to the invitation were interviewed by telephone. Participation at the interview was 87%. Kappa was 0.77 validating self-reported migraine in the questionnaire against the diagnosis of the clinical interview.

Results. Lifetime prevalences of migraine without aura, migraine with aura, migraine aura without headache, and migraine disorder were 8%, 4%, 1% and 1% in males and 16%, 7%, 3% and 2% in females. Overall lifetime prevalence of any type of migraine was 18%; 12% in males and 24% in females. This is lower than the sum of the prevalences since migraine diagnoses are not mutually exclusive. The male:female ratios of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were approximately 1:2.

Conclusions. Migraine is more prevalent than previously thought. There was a significant preponderance in females of all the subtypes of migraine except migrainous disorder.

Revised 1 November 1994


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