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© 1995 Oxford University Press

research-article

The Protective Effect of a Small Amount of Fish on Coronary Heart Disease Mortality in an Elderly Population

DAAN KROMHOUT, EDITH J M FESKENS and CAREL H BOWLES

Division of Public Health Research, National Institute of Public Health and Environmental Protection PO Box 1, 3720 BA, Bilthoven, The Netherlands.

Background. A protective effect of a small amount of fish on coronary heart disease (CHD) mortality has been establised in observational studies in middle-aged people. In the present study this association was investigated in the elderly

Methods. In 1971 CHD risk factors were measured in 272 people born before 1907. They belonged to a general pratice in Rotterdam, the Netherlands and were followed for 17 years. The cross-check dietary history method was used obtain information on fish comsumption.

Results. During the follow-up period 58 people died from CHD, 67 from cancer and 187 from all causes. In 1971 about 60% of the elderly ate fish and 40% did not eat fish. Multivariate Cox proportional hazards analyses, taking the confounding effect of major risk factor into account, showed an inverse relation between fish consumption and 17-year CHD mortally. The risk ratio (RR) for fish eaters compared with no-fish eaters was significantly different from unity (RR = 0.51, 95% Cl : 0.29–0.89). Cancer and total mortality were not related to fish consumption.

Conclusion. The result from the present study suggest that the protective effect of a small amount of fish in relation to CHD observed in middle-aged people seems also to be present in the elderly.

Received 1 October 1994


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