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© 1993 Oxford University Press

other

Spatial Correlation in Ecological Analysis

D G CLAYTON*, L BERNARDINELLI** and C MONTOMOLI**,{dagger}

* Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site Robinson Way, Cambridge CB2 2SR, UK
** Istituto Scienze Sanitarie Applicate, Università di Pavia via Bassi 21, 27100 Pavia, Italy
{dagger} Istituto di Igiene e Medicina Preventiva, Università di Sassari via Padre Manzella 4, 07100 Sassari, Italy

This paper presents a statistical approach, originally developed for mapping disease risk, to ecological regression analysis in the presence of spatial autocorrelated extra-Poisson variation. An insight into the effect of allowing for spatial autocorrelation on the relationship between disease rates and explanatory variables is given. Examples based on cancer frequency in Scotland and Sardinia are used to illustrate the interpretation of regression coefficient and further methodological issues.

Received 1 May 1993


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