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© 1993 Oxford University Press

other

Changes in Total Serum Cholesterol and Other Risk Factors for Cardiovascular Disease in Japan, 1980–1989

AKIRA OKAYAMA*,**, HIROTSUGU UESHIMA*, MICHAEL G MARMOT**, MASAKAZU NAKAMURA{dagger}, YOSHIKUNI KITA and MASANOBU YAMAKAWA*

* Department of Health Science, Shiga University of Medical Science Seta-Tsukinowa-cho, Ohtsu 520–21, Japan
** Department of Epidemiology and Public Health, University College Medical School 66–72 Gower Street, London WC1E 6EA, UK
{dagger} Department of Epidemiology and Mass Examination for Cardiovascular Disease, The Center for Adult Diseases Nakamichi, Higashinari-ku, Osaka 537, Japan

To monitor recent changes in Japan in diet and risk factors for cardiovascular disease (CVD), in the light of the decline on coronary heart disease, total serum cholesterol levels and other risk factors were compared between two nationwide health surveys in 1980 and 1989 conducted in the same population as the annual National Nutrition Surveys. Between 1980 and 1989, age-adjusted total serum cholesterol levels increased from 4.84 to 5.22 for men and from 4.91 to 5.24 mmol/l for women. Prevalence of age-adjusted hypercholesterolaemia of ≥5.68 mmol/l (220 mg/dl) increased from 15.8% to 29.4% for men and from 18.4% to 30.6% for women. Decline in blood pressure was observed for both sexes. Prevalence of smoking decreased from 64.7% to 58.7% in men while prevalence in women remained low (from 10.1 to 9.9%) Considerable increases in total serum cholesterol levels do not offer an explanation of the recent decline in mortality from coronary heart disease in Japan. This may, in part, be related to a decline in blood pressure levels

Received 1 June 1993


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