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© 1993 Oxford University Press

other

Hepatitis B Virus Infection among Pregnant Women in Northeastern Romania

BRADLEY A WOODRUFF*,, FLORIN POPOVICI**, NICOLAE BELDESCU**, CRAIG N SHAPIRO* and BRADLEY S HERSH{dagger}

* Hepatitis Branch, Division of Viral and Rickettsial Diseases, NCID, Centers for Disease Control Atlanta GA, USA
** Preventive Medicine Department, Romania Ministry of Health Romania
{dagger} Surveillance Branch, Division of HIV/AIDS, NCID, Centers for Disease Control Atlanta GA, USA

Reprint requests to: Bradley A Woodruff, PHS/Region IX, 50 United Nations Plaza, Room 349-A, San Francisco, CA 94102. USA

We conducted a serological survey of pregnant women attending prenatal clinics in northeastern Romania to determine the prevalence of hepatitis B virus (HBV) infection in this population. Overall, 162 (28%) of 573 women had evidence of past or current HBV infection, and 48 (8.4%) were carriers. The prevalence of past or current infection rose with age, but did not differ by educational level, occupation, or rural versus urban residence. Integration of hepatitis B vaccine into routine childhood immunization schedules, with the first dose given at birth, may have a substantial impact on HBV infection in Romania by preventing both perinatal and early childhood transmission.

Received 1 February 1993


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