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© 1993 Oxford University Press

other

Estimation of Vaccine Effectiveness Using the Screening Method

C P FARRINGTON

PHLS Communication Disease Surveillance Center 61 Colindale Avenue, London NW9 5EQ, UK

The screening method provides a simple and rapid way of estimating vaccine effectiveness. The paper diacuases the validity of the screening method with particular reference to bias and precision. Methods for correcting confounding, adjusting for covariates and over-dispersion, and deriving confidence limits are discussed in a modelling framework. The methods are illustratd using data on measles and pertussis vaccines.

Revised 1 January 1993


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