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© 1993 Oxford University Press

other

Ethnic and Gender Differences in the Prevalence of Anti-Cytomegalovirus Antibodies among Young Adults in Israel

MANFRED S GREEN*,**,{dagger},, DANI COHEN*, RAPHAEL SLEPON*, GUY ROBIN* and MICHAEL WIENER*

* Israel Defence Force Military Post 02149, Israel
** Occupational Health Institute Raanana, Israel
{dagger} Sackler Faculty of Medicine Tel Aviv University Israel

Reprint requests to: Dr Manfred Green, Occupational Health Institute, PO Box 3. Raanana 43100, Israel

The population of Israel comprises offspring of immigrants from countries of high and low incidence of cytomegaloviurs infection. To evaluate possible ethnic differences in the prevalence of antibodies against cytomegalovirus in young adults, blood samples were taken from a random sample of 422 Israeli military recruits aged 18–19 years, during 1987. Antibodies against cytomegalovirus were determined by means of ELISA. Subjects originating from North Africa or Asia had higher prevalences than those originating from Westem countries (84.0% and 74.0% versus 60.0%. P<0.001) and the differences persisted after adjustment for gender, education and socioeconomic status. The prevvalence of antibodies was significantiy lower in men than in women (63.1% versus76.5%). These findings identify subpopulations who are at incread risk of primary cytomegalovirus infection during adulthood and may be candidates for future anti-cytomegalovirus vaccines.

Revised 1 December 1992


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