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© 1993 Oxford University Press
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Physical Activity at Work and Cardiovascular Disease Risk: Results from the MONICA Augsburg Study
* GSF-Institut für Epidaniologie, Ingolstädter Landstr 1, D-8042 Neuherberg, Germany
Ruhr Universität Bochum D-4630 Bochum, Germany
In the MONICA Augsburg study the relationship between physical activity at work, cardiovascular risk factors, incidence of fatal and non-fatal myocardial infarction (MI) and total mortality was investigated in employed men. The MONICA Augsburg baseline survey of 1984/85 was designed as a crass-sectional study with follow-up. Physical activity was determined in 45–64 year dd men by interview (n=1074, =.83.6%) and by a 7-day activity diary (n=797, 62.0%). Employed men were categorized into an active vmus inactive group based on interview data on physical activity at work (P which had been validated against the 7day activity diary. When stratified by PAW, ege-adjusted means of diastolic (DBP) and systolic blood pressure (SBP) and total-cholesterol (T-C) were lower and the age-adjusted mean of HDL-cholesterol (HDL-C) was higher in active than in inactive men. A linear regrmsion model controlling for age, body mass index, alcohol consumption, smoking, and heart rate confirmed this relationship for physical activity at work; regmagion coefficients: DBP: ß=–2.33 (95% confidence interval [Cl] :–3.86-–0.91); SBP: ß=–2.87 (95% Cl : –5.22-–0.52); T-C: ß=-2.80 (95% Cl : –9.31-3.71); HDL-C: ß=;3.48 (95% Cl : 1.28-5.79). Survey participants were followed-up for a period of 6.8 years. The incidence density (per 1000 person-years) of fatal plus nonfatal MI was 6.8 for active men versus 5.9 for inactive men; the incidence density for total mortality was 11.2 versus 5.9, respectively. After controlling for hypertension, T-C and smoking in a Cox proportional hazards model the relative risk of active compard to inactive men was 1.28 (95% CI : 0.68–2.55) for MI incidence and 1.91 (95% CI : 0.98–3.73) for total mortality. Adjustment for educational level did not significantly change the relative riske. In spite of the beneficial effect of PAW, on cardiovascular risk factors found in cross-sectional analysis, we observed a higher MI incidence and total mortality risk in the longitudinal analyses. The mast likely occupational or social factors. explanation appears to be strong confounding by occupational or social factors.
Revised 1 January 1993
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