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© 1993 Oxford University Press

other

Radon Exposure and Leukaemia in Adulthood

JEAN-FRANžOIS VIEL

Deparment of Public Health, Biostatistics and Epidemiology Unit Faculty of Medicine 2 place Saint-Jaeques, 25330 Besanžon, France

Positive associations between leukaemia and radon concentrations have been observed in England, Scotland and Wales, and Canada. Results of a similar study for the populations of 41 French administrative areas (‘départements’) are reported for 1984–1986. The average indoor radon and gamma ray concentrations per ‘départements’ range from 12 to 147 Bq.m–3 and from 28 to 142 nG.h–1, respectively. Acute lymphoid leukaemia mortality rate is similar to the national level, whereas an excess of acute myeloid leukaemia deaths is observed. According to Poisson regression models and modified tests for partial correlation, acute myeloid leukaemia mortality is significantiy and pmitiveiy related to indoor radon concentration whether or not adjustment is made for indoor gamma ray dose, socioeconomic status and linear gradient. This result reinforces the evidence that indoor exposure to high levels of radon is a leukaemic environmental hazard.

Revised 1 December 1992


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