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© 1993 Oxford University Press

other

Serepidemiology of Hepatitis B and D Virus Infection among Intravenous Drug Addicts in Israel

MICHAEL DAN*, MEIR ROCK*, PEARL LILOS{dagger} and SHULAMIT BAR SHANY{ddagger}

* Infectious Diseases Unit, The E Wolfson Hospital Holon 58100, Israel
{dagger} Statistics Laboratory, Department of Mathematics, Tel Aviv University
{ddagger} the MDA Blood Services Tel Hashomer, Israel

To evaluate the prevalence of hepatitis B virus (HBV) and hepatitis D virus (HDV) infection among intravenous drug addicts (IVDA) in Israel, serum samples were collected from 400 asymptomatic individuals attending a methadone clinic in Tel Aviv. Overall 5.5% were HBsAg positive, 2.4% HBeAg positive, 52% anti-HBc positive and 6.6% were positive for anti-HD. Anti-HD was identified in 18% of addicts who were HBsAg positive and in 3% who were HBsAg negative and anti-HBc positive. Strong correlation was found between positivity to HBV antibodies and age and duration of drug use. History of jaundice correlated more strongly with anti-HD positivity than with presence of antibodies to HBV. We conclude that Israeli IVDA are less exposed to HBV and HDV infection than their North American and European counterparts.

Received 1 July 1992


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