| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
© 1992 Oxford University Press
research-article |
Smoking and Lung Cancer in China: Combined Analysis of Eight Case-Control Studies
Institute of Environmental Health and Engineering, Chinese Academy of Preventive Medicine 29 Nan Wei Road, Beijing 100050, People's Republic of China
Smoking is well established as a principal risk factor for lung cancer. The risk of lung cancer is about ten times higher in smokers in Western countries. In China, a number of epidemiological studies have investigated the association between lung cancer and smoking and in the present paper, a combined analysis of eight such case-control studies is described. The summary odds ratio (OR), calculated by the Mantel-Haenszel method, and attributable risk (AR) of lung cancer associated with smoking were calculated from the combined data which were obtained from a literature review. The eight case-control studies were conducted in Beijing, Shanghai, Shenyang, Nanjing, Harbin, Zhengzhou, Taiyuan, and Nanchang, yielding a total of 4081 lung cancer cases and 4338 controls. The summary OR of lung cancer associated with smoking was 2.17 (95% Cl (confidence interval): 1.98–2.39). The OR were 3.09(95% Cl: 2.61–3.66) for males and 2.30 (95% Cl: 1.96–2.69) for females. The AR were 38.2% for both sexes, 56.7% for males and 25.5% for females. Risks of 1.00, 1.03, 2.04, and 3.33 showed a dose-response relationship between lung cancer and number of cigarettes smoked per day. There were also significant dose-response relationships of lung cancer with duration of smoking (OR = 1.00, 1.02, 2.66), and age at start of smoking (OR = 1.00, 3.30, 2.36, 1.18). The OR and AR of lung cancer associated with smoking in China were much lower than those reported in Western countries and the possible reasons for this are discussed.
Received 1 July 1991
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  Han Zao Li, Weixing Sun, Fangmei Cheng, Xiangrong Wang, Weiping Liu, and Aisheng Wang Cigarette Smoking Status and Smoking Cessation Counseling of Chinese Physicians in Wuhan, Hubei Province Asia Pac J Public Health, July 1, 2008; 20(3): 183 - 192. [Abstract] [PDF]
|
|
|
|
 |
|
 P. Pisani, P. Srivatanakul, J. Randerson-Moor, S. Vipasrinimit, S. Lalitwongsa, P. Unpunyo, S. Bashir, and D. T. Bishop GSTM1 and CYP1A1 Polymorphisms, Tobacco, Air Pollution, and Lung Cancer: A Study in Rural Thailand. Cancer Epidemiol. Biomarkers Prev., April 1, 2006; 15(4): 667 - 674. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Hu, C. Galeone, R. Lui, C. Pelucchi, C. L. Vecchia, and E. Negri Smoking and lung cancer in Harbin, northeast China Ann. Onc., October 1, 2005; 16(10): 1605 - 1608. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F D K Liddell and P Lee Joint action of smoking and asbestos exposure on lung cancer * Author's reply Occup. Environ. Med., July 1, 2002; 59(7): 494 - 495. [Full Text] [PDF]
|
|
|
|
 |
|
 Q. Lan, R. S. Chapman, D. M. Schreinemachers, L. Tian, and X. He Household Stove Improvement and Risk of Lung Cancer in Xuanwei, China J Natl Cancer Inst, June 5, 2002; 94(11): 826 - 835. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. V Brenner, Z. Wang, R. A Kleinerman, L. Wang, S. Zhang, C. Metayer, K. Chen, S. Lei, H. Cui, and J. H Lubin Previous pulmonary diseases and risk of lung cancer in Gansu Province, China Int. J. Epidemiol., February 1, 2001; 30(1): 118 - 124. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Seow, B. Zhao, W.-T. Poh, M. Teh, P. Eng, Y.-T. Wang, W.-C. Tan, E. J.D. Lee, and H.-P. Lee NAT2 slow acetylator genotype is associated with increased risk of lung cancer among non-smoking Chinese women in Singapore Carcinogenesis, September 1, 1999; 20(9): 1877 - 1881. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Z. Li, D. Fish, and X. Zhou Increase in cigarette smoking and decline of anti-smoking counselling among Chinese physicians: 1987-1996 Health Promot. Int., June 1, 1999; 14(2): 123 - 131. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B.-Q. Liu, R. Peto, Z.-M. Chen, J. Boreham, Y.-P. Wu, J.-Y. Li, T C. Campbell, and J.-S. Chen Emerging tobacco hazards in China: 1. Retrospective proportional mortality study of one million deaths BMJ, November 21, 1998; 317(7170): 1411 - 1422. [Abstract] [Full Text]
|
|