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International Journal of Epidemiology, Vol 20, S4-12, Copyright © 1991 by International Epidemiological Association

ARTICLES

Risk factors for Alzheimer's disease: overview of the EURODEM collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group

CM van Duijn, T Stijnen and A Hofman
Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.

Studies of risk factors for Alzheimer's disease have been hampered by low statistical power. The data from 11 case-control studies were pooled and re-analysed to evaluate the evidence for the association of Alzheimer's disease with family history of dementia and related disorders, parental age, medical history, and environmental factors. This paper gives a brief description of the participating studies and discusses the strategy that has been followed in the collaborative analysis.
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