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© 1991 Oxford University Press

research-article

Prevalence of Diabetes Mellitus and Impaired Glucose Tolerance in the Middle-Aged Population of Three Areas in Finland

JAAKKO TUOMILEHTO*, HEIKKI J KORHONEN*, LEENA KARTOVAARA*, VEIKKO SALOMAA*, JARI H STENGÅRD*, MATTI PITKÄNEN*, ANTTI ARO**, KAIJA JAVELA**, MATTI UUSITUPA{dagger} and JANNE PITKÄNIEMI*

*Department of Epidemiology, National Public Health Institute Elimaenkatu 25, 6th Floor, 00510 Helsinki, Finland.
**Department of Biochemistry, National Public Health Institute Mannerheimintie 166, 00300 Helsinki.
{dagger}Department of Clinical Nutrition, University of Kuopio Kuopio, Finland.

The prevalence of diabetes mellitus and impaired glucose tolerance (IGT) was determined in a random sample of the population aged 45–64 years in three areas of Finland. The two-hour oral glucose tolerance test was repeated in subjects whose first test suggested abnormal glucose tolerance. In the final classification, based on the results of the two tests, the age-standardized prevalence of diabetes, according to the WHO criteria was 5.7% (95% confidence interval (Cl): 4.3–7.1) in men and 4.6% (95% Cl: 3.6–5.0) in women. The prevalence of IGT was 3.1% (95% Cl: 2.1–4.1) in men and 5.1% (95% Cl: 3.9–6.3) in women. Among those aged 55–64 years the prevalence was 6.9% in men and 7.5% in women. The prevalence of diabetes and IGT were not different between the three areas. The age-specific mean values of fasting and two-hour blood concentrations and the 90th percentiles of the blood glucose distributions were also not different between the areas. The prevalence of IGT and diabetes increased with age more steeply among women than men. The median of fasting blood glucose did not change, but the 90th percentile increased with increasing age. The entire distribution of two-hour blood glucose shifted towards higher values with ageing, but the major increase was seen for the 95th percentile. The majority of the diabetic subjects were aware of their condition. The awareness was better among men than women.

Revised 1 April 1991


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