Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by LAMONT, D W
Right arrow Articles by REID, D
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by LAMONT, D W
Right arrow Articles by REID, D
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1991 Oxford University Press

research-article

Primary Hepatocellular Carcinoma in an Area of Low Incidence: Evidence for a Viral Aetiology from Routinely Collected Data

D W LAMONT*, K A BUCHAN**, C R GILLIS* and D REID{dagger}

*West of Scotland Cancer Surveillance Unit, Greater Glasgow Health Board, Ruchill Hospital Glasgow G20 9NB, UK.
**Department of Microbiology and Infectious Diseases, Health Science Centre. University of Calgary Alberta, T2N 9T2, Canada (on secondment to the Communicable Diseases (Scotland) Unit 1986–1987)
{dagger}Communicable Diseases (Scotland) Unit, Ruchill Hospital Glasgow G20 9NB, UK.

In recent years a strong case has been made in support of a viral aetiology for at least some primary hepatocellular carcinoma (PHC) in areas of low incidence. By pooling routinely collected cancer registration and infection data, study of the relationship between hepatitis B virus (HBV) infection and the incidence of PHC in Scotland over the period 1972–1985 has confirmed this view. Over this period the incidence of PHC in men increased, there was a relationship between the incidence of notification of HBV infection and that of hepatocellular carcinoma in different parts of the country, and an increased risk attached to those chronically infected with the virus. Given the recent introduction of lower cost yeast derived vaccines, there may now be more scope for prevention both of primary liver cancer and of other liver disease.

Revised 1 September 1990


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.