International Journal of Epidemiology, Vol 19, S8-10, Copyright © 1990 by International Epidemiological Association
DT Carr
Lung cancer is a complex problem because there are a number of different
histological cell types. Those commonly grouped as bronchogenic carcinoma
(epidermoid carcinoma, adenocarcinoma, large cell undifferentiated
carcinoma, small cell carcinoma, and adenosquamous carcinoma) account for
more than 90% of the new cases and the deaths each year. The natural
history of bronchogenic carcinoma suggests that many years pass while the
cancer evolves from a pre- cancerous change in the bronchial mucosa, to
undetectable microscopic cancer, to preclinical asymptomatic cancer and
finally into a full symptomatic cancer, the phase of most lung malignancies
in the tissue at diagnosis. Therefore, students of the aetiology of this
disease must consider what has happened to patients 5-20 years before lung
cancer is diagnosed.
ARTICLES
Histopathology of lung cancer
Department of Internal Medicine, MD Anderson Hospital and Tumor Institute, University of Texas System Cancer Center, Houston.
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