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© 1988 Oxford University Press

research-article

An Outbreak of Foodborne Hepatitis A in a Factory: A Possible Shift in Age of Patients in Japan

HISAO HAYASHI*, AKIRA YAGI*, HIROSHI ICHIMIYA*, TOMOYUNKI HIGUCHI*, AKIHIKO FUJI*, SHINICHI KAKUMU*, NOBUO SAKAMOTO*, SHIGERU KATO{dagger}, HIROTO KATO{dagger}, GIICHIROU MORI{dagger} and KUNIKI SHIMIZU{dagger}

*Third Department of Medicine, Nagoya University School of Medicine Tsuruma-cho Showa-ku, Nagoya 466 Japan
{dagger}Environmental Sanitation Division, Department of Health, Aichi Prefectural Government Naka-ku, Nagoya 460, Japan

Hayashi H (Third Department of Medicine, Nagoya University School of Medicine Tsuruma-cho, Showa-ku, Nagoya 466, Japan), Yagi A, Ichimiya H, Higuchi T, Fuji A, Kakumu S, Sakamoto N, Kato S, Kato H, Mori G and Shimizu K. An outbreak of foodborne hepatitis A in a factory: a possible shift in age of patients in Japan. International Journal of Epidemiology 1988, 17: 870–873.

We investigated extensively an outbreak of hepatitis A at a factory in suburban Nagoya. Epidemiological study indicated a foodborne outbreak by a supplier of lunches. Serologically, all the employees younger than 30 years of age had been susceptible to hepatitis A virus, but the highest morbidity was observed in the 40–44 age group. The age difference in morbidity from foodborne hepatitis and susceptible populations suggests a shift in mean patient age linked to a shift in antibody prevalence to hepatitis A virus. In communities where the prevalence started shifting after development of sanitary systems, effective prophylaxis for foodborne hepatitis A will be necessary to prevent the disease in an increasing number of older patients in a few decades.

Received 1 January 1988


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