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© 1988 Oxford University Press

research-article

The Relation of Respiratory Symptoms and Ventilatory Function to Moderate Occupational Exposure in a General Population

Results from the French PAARC study of 16000 adults

MICHAL KRZYZANOWSKI* and FRANCINE KAUFFMANN{dagger}

*National Institute of Hygiene Chocimska St 24 PL-00791 Warsaw, Poland
{dagger} INSERM Unit 169, Villejuif, France

Data from the French PAARC (Pollution Atmosphérique et Affections Respiratoires Chroniques) study were used to assess the effect of a priori moderate occupational exposure to dust, gases or chemical fumes on the prevalance of respiratory symptoms and ventilatory function. In this community-based population, without households ‘headed’ by manual workers, 34% of the 8692 men and 23% of the 7772 women, 25–59 years of age, ever occupationally active, reported some exposure. The studied relationships were adjusted for age, height smoking habits, socio-occupational class, education and air pollution by logistic or linear regression methods. For men and women, some 50% increase (p<0.01) in chronic cough, chronic bronchitis, dyspnoea grade 2 and wheezing prevalence was observed in the exposed group compared to the never exposed, with the strongest association for wheezing. FEV1 and FEF25–75% were not associated with occupational exposure. Among men, FEV1/FVC and FEF25–75%/FVC were significantly lower (p<0.001 and p<0.05) among the exposed compared to never exposed, but FVC was significantly greater (p<0.05). Among women, occupational exposure was significantly related to a lower FEV1/FVC in the subgroup with a history of asthma or wheezing. Results suggest that occupational exposures of relatively low intensity, encountered in the nonindustrial work places may constitute a non-negligeable risk for respiratory health.

Revised 1 May 1987


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