Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (30)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by FUNG, K. Y.
Right arrow Articles by HOWE, G. R
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by FUNG, K. Y.
Right arrow Articles by HOWE, G. R
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1984 Oxford University Press

research-article

Methodological Issues in Case-Control Studies III:—The Effect of Joint Misclassification of Risk Factors and Confounding Factors upon Estimation and Power

KAREN YUEN FUNG* and GEOFFREY R HOWE**,{dagger}

*Department of Mathematics, University of Windsor Windsor, Ontario, Canada
**NCIC Epidemiology Unit, Faculty of Medicine, McMurrich Building, University of Toronto Toronto, Canada M5S 1A8

{dagger}Requests for reprints should be addressed to G. R. Howe.

The effect of joint misclassification of polytomous risk factors and polytomous covariates in case-control studies upon estimation and power has been examined using computer simulation and mathematical models. It is concluded that non-differential misclassification of covariates may be as important as non-differential misclassification of exposure variables, and that the resultant bias of the relative risk estimate may be either toward or away from the null. It is pointed out that when a confounding variable is misclassified the calculated p value from the particular study will be incorrect and may either be too large or too small depending on the nature of the confounding.

Received 1 September 1983


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am J EpidemiolHome page
G. E. Fraser and D. O. Stram
Regression Calibration in Studies with Correlated Variables Measured with Error
Am. J. Epidemiol., November 1, 2001; 154(9): 836 - 844.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
J. Merlo, G. Berglund, E. Wirfalt, B. Gullberg, B. Hedblad, J. Manjer, B. Hovelius, L. Janzon, B. S. Hanson, and P. O. Ostergren
Self-administered Questionnaire Compared with a Personal Diary for Assessment of Current Use of Hormone Therapy: An Analysis of 16,060 Women
Am. J. Epidemiol., October 15, 2000; 152(8): 788 - 792.
[Abstract] [Full Text] [PDF]

Home page
 Educational and Psychological MeasurementHome page
D. L. Streiner and H. R. Miller
Maximum Likelihood Estimates of the Accuracy of Four Diagnostic Techniques
Educational and Psychological Measurement, September 1, 1990; 50(3): 653 - 662.
[Abstract]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.