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© 1983 Oxford University Press

research-article

Correcting for Misclassification in Two-Way Tables and Matched-Pair Studies

SANDER GREENLAND*, C ERICSON* and DAVID G KLEINBAUM{dagger}

*Division of Epidemiology, School of Public Health, University of California Los Angeles, CA 90024, USA
{dagger}t Department of Biostatistics, School of Public Health, University of North Carolina Chapel Hill, NC 27514, USA

Barron1 has presented a matrix formula that allows correction for nondifferential misclassification in two-by-two tables. We show how extensions of his result can be applied to situations involving differential misclassification, matched data, and arbitrary two-way tables. We also discuss some important limitations in the application of algebraic corrections for misclassification. In particular, we show that study misclassification rates need not reflect population misclassification rates if the distribution of the misclassified variable is determined by aspects of the study design.

Received 1 March 1982


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